Early use assessments
We offer rapid assessment of early-stage technologies based on clinical effectiveness and value for money, allowing patients and services to benefit sooner from promising technologies where the evidence base is still developing.
Routine use assessments
This work is focused on technologies with an established evidence base which may be ready for widespread adoption into the NHS:
Existing use assessments
This is a new process focussing on post-market assessment of technologies available to the NHS to ensure they still represent good value.
Regulatory documentation
We support NICE by identifying technologies which are indicated for a particular procedure. This involves liaising with the company, reviewing regulatory documentation – for example CE certificate, declaration of conformity and instruction for use – before summarising the findings.
There are currently no projects underway in this area.
Other work
Pilot projects
The Horizon Europe’s ASSESS DHT project aims to increase the adoption of trustworthy, effective digital health technologies through the development of robust, harmonised assessment methodologies. The team was commissioned to carry out a pilot assessment using the draft methodologies and give feedback.
Publications
| Tables | Authors | Source |
| Current Practice, Safety and Efficacy of Interventions for Recurrent Respiratory Papillomatosis: Evidence From a UK Registry. | Donne AJ, Keltie K, Burn J, Belilios E, Powell S, Cognigni P, Nixon IJ, Bateman N, Kubba H, Judd O, Sims A. | Clin Otolaryngol. 2024 Oct 24. doi: 10.1111/coa.14245. Epub ahead of print. PMID: 39445512 |
| Infection after ureteroscopy for ureteric stones: analysis of 71 305 cases in the Hospital Episode Statistics database. | Veeratterapillay R, Gravestock P, Harding C, Shaw M, Fitzpatrick J, Keltie K, Cognigni P, Sims A, Rogers A. | BJU Int. 2023 Jan;131(1):109-115. doi: 10.1111/bju.15850. Epub 2022 Aug 12. PMID: 35844154. |
| Our experience in developing and operating the Airway Intervention Registry for Recurrent Respiratory Papillomatosis (AIR-RRP): national data collection | Sims A, Keltie K, Belilios E, Burn J, Brown L, Jackson A, Powell S, Jones S, Donne A | NIHR Open Res. 2023 Jan 12;2:22 |
| Impact on stable chest pain pathways of CT fractional flow reserve | O’Leary RA, Burn J, Urwin SG, Sims AJ, Beattie A, and Bagnall A | Heart. 2023 |
| National Cohort Study of Health Care Resource Use After Pediatric Tracheostomy. | Powell J, Keltie K, Sims A, Richardson H, Brodlie M, Powell S. | JAMA Pediatr. 2022 Aug 1;176(8):817-819; |
| Patent foramen ovale closure: A prospective UK registry linked to hospital episode statistics. | Willits I, Keltie K, Henderson R, de Belder M, Linker N, Patrick H, Powell H, Berry L, Urwin S, Cole H, Sims AJ. | PLoS One. 2022 Jul 14;17(7):e0271117; |
| Coblation intracapsular tonsillectomy: A cohort study of NHS practice in England using Hospital Episode Statistics | Powell S, Tweedie DJ, Jonas NE, Bateman ND, Keltie K, Sims AJ. | Clin Otolaryngol. 2022 May;47(3):471-477; |
| Left atrial appendage occlusion in the UK: prospective registry and data linkage to Hospital Episode Statistics | Willits I, Keltie K, Linker N, de Belder M, Henderson R, Patrick H, Powell H, Berry L, Urwin SG, Cole H, Sims AJ. | Eur Heart J Qual Care Clin Outcomes. 2021b Sep 16;7(5):468-475 |
| Safety, effectiveness and costs of percutaneous mitral valve repair: A real-world prospective study | Willits I, Keltie K, de Belder M, Henderson R, Linker N, Patrick H, Powell H, Berry L, Speller J, Urwin SG, Cole H, Sims AJ. | PLoS One. 2021a May 12;16(5):e0251463; |
| Comparison of identifiable and non-identifiable data linkage: health technology assessment of MitraClip using registry, administrative and mortality datasets | Keltie K, Cognigni P, Gross S, Urwin S, Burn J, Cole H, Berry L, Patrick H, Sims A. | BMJ Health Care Informatics. 2021 Apr;28(1):e100223. |
| Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episode statistics. | Page T, Veeratterapillay A, Keltie K et al. | BMC Urol. 2021; 21(1): 55. |
| Paediatric tonsillectomy in england a cohort study of clinical practice and outcomes using Hospital Episode Statistics data (2008â€2019) | Keltie K, Donne A, Daniel M, Stephenson K, Qyatt M, Kuo M, Saunders M, Kumar NB, Philpott CM, Bruce I, Smith ME, Hardman JC, Cognigni P, Richardson H, Gross S, Sims AJ, Powell S. | Clinical Otolaryngology 2021; 46(3): 552-561 |
| Balloon dilatation for paediatric airway stenosis: Evidence from the UK Airway Intervention Registry | Powell S, Keltie K, Burn J, Cole H, Donne A, Morrison G, Stephenson K, Daniel M, Gupta S, Wyatt M, Patrick H, Sims A. | Clin Otolaryngol. 2020 May;45(3):334-341; |
| Prevalence and management of recurrent respiratory papillomatosis (RRP) in the UK: cross-sectional study | Donne AJ, Keltie K, Cole H, Sims AJ, Patrick H, Powell S. | Clin Otolaryngol. 2017 Feb;42(1):86-91. doi: 10.1111/coa.12683. Epub 2016 Jun 19. PMID: 27208548. |
| Complications following tension-free vaginal tape (TVT), trans-obturator tape (TOT) and suprapubic sling (SS) procedures for stress urinary incontinence: 8-year retrospective cohort of 92,246 women in England | Keltie K, Elneil S, Monga A, Patrick H, Powell J, Campbell B, Sims AJ | Scientific Reports 2017; 7(12015) |
| Effects of procedure volume on outcomes after iliac artery angioplasty and stenting | Goode SD, Keltie K, Burn J, Patrick H, Cleveland T, Campbell B, Gaines P, Sims AJ | 2013; Br J Surg. 2013; 100(9): 1189-96 |
