Early value assessments
We offer rapid assessment of early-stage technologies based on clinical effectiveness and value for money, allowing patients and services to benefit sooner from promising technologies where the evidence base is still developing.
| Title | Publication date |
| GID-HTE10065 Algorithms applied to spirometry to support the diagnosis of lung conditions in primary care and community diagnostic centre | Ongoing |
| Contributing to: GID-HTE10063 Digital technologies to support asthma self-management | |
| GID-HTE10059 Artificial intelligence technologies to aid the opportunistic detection of vertebral fragility fractures | October 2025 |
| · GID-HTE10043 Robot-assisted surgery for orthopaedic procedures | April 2025 |
| GID-HTE10007 Digital products for diet and activity support alongside prescription of weight loss medication | October 2023 |
| GID-MT590 ProKnow Cloud-based system for radiotherapy data archiving, communications and management | March 2023 |
Assessment reports
This work is focused on technologies with an established evidence base which may be ready for widespread adoption into the NHS:
Late stage assessments
This is a new process focussing on post-market assessment of technologies available to the NHS to ensure they still represent good value.
| Title | Publication date |
| HTE31, Transcatheter aortic valve implants for people with aortic stenosis | August 2025 |
| HTE28, Intermittent urethral catheters for long-term urinary management in adults | July 2025 |
Regulatory documentation
We support NICE by identifying technologies which are indicated for a particular procedure. This involves liaising with the company, reviewing regulatory documentation – for example CE certificate, declaration of conformity and instruction for use – before summarising the findings.
There are currently no projects underway in this area.
Other work
Publications
| Title | Authors | Source |
| Complications following tension-free vaginal tape (TVT), trans-obturator tape (TOT) and suprapubic sling (SS) procedures for stress urinary incontinence: 8-year retrospective cohort of 92,246 women in England | Keltie K, Elneil S, Monga A, Patrick H, Powell J, Campbell B, Sims AJ | Scientific Reports 2017; 7(12015)) |
| Infection after ureteroscopy for ureteric stones: analysis of 71 305 cases in the Hospital Episode Statistics database. | Veeratterapillay R, Gravestock P, Harding C, Shaw M, Fitzpatrick J, Keltie K, Cognigni P, Sims A, Rogers A. | BJU Int. 2023 Jan;131(1):109-115. doi: 10.1111/bju.15850. Epub 2022 Aug 12. PMID: 35844154. |
| National Cohort Study of Health Care Resource Use After Pediatric Tracheostomy. | Powell J, Keltie K, Sims A, Richardson H, Brodlie M, Powell S. | JAMA Pediatr. 2022 Aug 1;176(8):817-819; |
| Paediatric tonsillectomy in england a cohort study of clinical practice and outcomes using Hospital Episode Statistics data (2008â€2019) | Keltie K, Donne A, Daniel M, Stephenson K, Qyatt M, Kuo M, Saunders M, Kumar NB, Philpott CM, Bruce I, Smith ME, Hardman JC, Cognigni P, Richardson H, Gross S, Sims AJ, Powell S. | Clinical Otolaryngology 2021; 46(3): 552-561 |
| Coblation intracapsular tonsillectomy: A cohort study of NHS practice in England using Hospital Episode Statistics | Powell S, Tweedie DJ, Jonas NE, Bateman ND, Keltie K, Sims AJ. | Clin Otolaryngol. 2022 May;47(3):471-477; |
| Prostatic urethral lift (UroLift): a real-world analysis of outcomes using hospital episode statistics. | Page T, Veeratterapillay A, Keltie K et al. | BMC Urol. 2021; 21(1): 55. |
| Effect of procedure volume on outcomes after iliac artery angioplasty and stenting. | Goode SD, Keltie K, Burn J, Patrick H, Cleveland T, Campbell B, Gaines P, Sims AJ. | 2013; Br J Surg. 2013; 100(9): 1189-96 |
| Safety, effectiveness and costs of percutaneous mitral valve repair: A real-world prospective study | Willits I, Keltie K, de Belder M, Henderson R, Linker N, Patrick H, Powell H, Berry L, Speller J, Urwin SG, Cole H, Sims AJ. | PLoS One. 2021a May 12;16(5):e0251463; |
| Comparison of identifiable and non-identifiable data linkage: health technology assessment of MitraClip using registry, administrative and mortality datasets | Keltie K, Cognigni P, Gross S, Urwin S, Burn J, Cole H, Berry L, Patrick H, Sims A. | BMJ Health Care Informatics. 2021 Apr;28(1):e100223. |
| Left atrial appendage occlusion in the UK: prospective registry and data linkage to Hospital Episode Statistics | Willits I, Keltie K, Linker N, de Belder M, Henderson R, Patrick H, Powell H, Berry L, Urwin SG, Cole H, Sims AJ. | Eur Heart J Qual Care Clin Outcomes. 2021b Sep 16;7(5):468-475 |
| Patent foramen ovale closure: A prospective UK registry linked to hospital episode statistics. | Willits I, Keltie K, Henderson R, de Belder M, Linker N, Patrick H, Powell H, Berry L, Urwin S, Cole H, Sims AJ. | PLoS One. 2022 Jul 14;17(7):e0271117; |
| Balloon dilatation for paediatric airway stenosis: Evidence from the UK Airway Intervention Registry | Powell S, Keltie K, Burn J, Cole H, Donne A, Morrison G, Stephenson K, Daniel M, Gupta S, Wyatt M, Patrick H, Sims A. | Clin Otolaryngol. 2020 May;45(3):334-341; |
| Current Practice, Safety and Efficacy of Interventions for Recurrent Respiratory Papillomatosis: Evidence From a UK Registry. | Donne AJ, Keltie K, Burn J, Belilios E, Powell S, Cognigni P, Nixon IJ, Bateman N, Kubba H, Judd O, Sims A. | Clin Otolaryngol. 2024 Oct 24. doi: 10.1111/coa.14245. Epub ahead of print. PMID: 39445512 |
| Our experience in developing and operating the Airway Intervention Registry for Recurrent Respiratory Papillomatosis (AIR-RRP): national data collection. | Sims A, Keltie K, Belilios E, Burn J, Brown L, Jackson A, Powell S, Jones S, Donne A | NIHR Open Res. 2023 Jan 12;2:22 |
| Prevalence and management of recurrent respiratory papillomatosis (RRP) in the UK: cross-sectional study | Donne AJ, Keltie K, Cole H, Sims AJ, Patrick H, Powell S. | Clin Otolaryngol. 2017 Feb;42(1):86-91. doi: 10.1111/coa.12683. Epub 2016 Jun 19. PMID: 27208548. |
| Our experience in developing and operating the Airway Intervention Registry for Recurrent Respiratory Papillomatosis (AIR-RRP): national data collection | Sims A, Keltie K, Belilios E, Burn J, Brown L, Jackson A, Powell S, Jones S, Donne A | NIHR Open Res. 2023 Jan 12;2:22 |
| Impact on stable chest pain pathways of CT fractional flow reserve | O’Leary RA, Burn J, Urwin SG, Sims AJ, Beattie A, and Bagnall A | Heart. 2023 |
