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Home > About Newcastle Hospitals > Information leaflets and helpful resources > In vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) – information for patients having treatment > Multiple pregnancy and single embryo transfer

Multiple pregnancy and single embryo transfer

On this page

  1. Why am I being asked about this?
  2. What is the risk to the baby of being a twin?
  3. What is the risk to the mother of a twin pregnancy?
  4. Who should have a single embryo transfer?
  5. What is the change in pregnancy rate if I have only one embryo transferred?

Why am I being asked about this?

Patients needing fertility treatment often consider that having 2 healthy babies in a twin pregnancy is the best outcome of treatment, but there are risks in a twin pregnancy and you need to be aware of them. 

The overall chance of twin pregnancy remains significant if 2 embryos are replaced.  All clinics are now required by our regulators, the HFEA, to reduce this multiple pregnancy rate.  We are thus giving you some information here to help you decide whether to have one or two embryos transferred.

What is the risk to the baby of being a twin?

Being a baby in a twin pregnancy is more risky. 

The chance of a baby dying between 24 weeks of pregnancy and 7 days after birth (perinatal mortality rate) is:

  • Singleton (one baby): 6.9 in 1000
  • Twin (two babies):  27.2 in 1000

The chance of a baby having cerebral palsy is:

  • Singleton (one baby): 2.3 in 1000
  • Twin (two babies): 12.6 in 1000

What is the risk to the mother of a twin pregnancy?

Almost all complications of pregnancy for the mother are increased in a twin pregnancy. This includes premature delivery, problems with blood pressure, bleeding, Caesarean section and blood clots.  In addition, don’t forget that looking after twins, even if they and you are fit and well, is much more difficult.

Who should have a single embryo transfer?

Those women with the greatest risk of twins are 37 or younger and are having their first treatment.  This does not mean that twins do not occur in women over 37 years but it is less likely.

We can only give you a realistic estimate of your risk of twins when we know more about your embryos. That will not be until 5 days after the eggs are collected.

What is the change in pregnancy rate if I have only one embryo transferred?

Evidence shows that if you have only one embryo transferred and you have other embryos frozen and transferred later if required, your overall chance of a baby is not reduced.

If you wish to know more about our research, we would be happy to discuss this with you when you come to the clinic.

Contact

If you have any questions or concerns throughout your treatment, you can email the fertility nurses.

We do our best to answer your call as soon as possible, but we are a very busy service, so we may not always have someone available to speak with you immediately. If the line is engaged, please try again later or use the nurse email address above. The telephone line is often quieter in the afternoon.

Outside of these hours, there is an on-call doctor available to speak to in emergencies only on 0191 256 8240. The on-call doctor is not able to change clinic appointments or to answer general queries that are not urgent. These types of calls must be made during clinic opening hours.

[email protected]

For more urgent queries, our telephone line is open 8am to 4.30pm Monday to Friday

0191 213 8213

Patient feedback

We welcome your opinions and feedback on areas you feel have gone well or suggestions you may have to help us improve our service.

If you have any problems during your treatment or are unhappy with the care you are receiving please contact the Senior Sister (Stacey Turnbull) on 0191 213 8213.

Fertility treatment is sometimes upsetting and frustrating particularly when things do not go quite to plan or you do not get the outcome you had hoped for. Sometimes having a chat with us will help relieve some of the tension and frustrations you may be feeling. We are always willing to listen.

Data sources

  • World Health Organization (WHO),
  • Human Fertilisation & Embryology Authority (HFEA) & Local Policies
Page last updated: 30/10/2026

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