Dental experts at Newcastle Hospitals and Newcastle University are leading a new study to determine how nicotine pouches affect oral health.
Limited research available
Nicotine pouches are small sachets that are placed between the lip and gum and release nicotine into the bloodstream.
They are thought to be less toxic than cigarettes, however limited research means long-term side effects have not been determined.
The use of nicotine pouches in the UK has increased over recent years. Current research also indicates that awareness of nicotine pouches is rising amongst adults and children1.
As part of the study, participants will be asked to complete a short, anonymous online survey that collects information about their nicotine pouch use and any changes they may have noticed to the teeth or gums.
Participants will also have the option to submit photos of the inside of their mouth. This will help researchers to assess whether any changes in the gums, cheeks, or tongue are associated with nicotine pouch use.
The study is led by the National Institute for Health and Care Research Dental Research Facility (NIHR Dental CRF) Newcastle, based at Newcastle’s dental hospital.
First-of-its-kind study
Dr Richard Holliday, honorary consultant in restorative dentistry at Newcastle Hospitals and senior lecturer at Newcastle University, is overseeing the study. He said:
“The use of nicotine pouches as an alternative to smoking and vaping has increased in recent years.

“Although nicotine pouches are tobaccoâfree, there remains a lack of robust, independent research on their longâterm impact on oral health.
“This first-of-its-kind study will help us to gather much-needed information to inform future health guidance.”
Dental professionals invited to take part
Dentists will also be given the opportunity to take part in the survey where they can report clinical features that they have noticed in patients using nicotine pouches.
A small number of participants will be invited to attend the NIHR Dental CRF for clinical tests, including biopsies of the mouth, if required.
The study is funded by the Oral and Dental Research Trust and the British Society for Oral and Dental Research.